Yes, it is one of the drawbacks, but thankfully in my case at least, it’s been pretty rare. I think I have had the luer lock disconnect thing twice in 17 years.
I have also run out of insulin in the cartridge at least once (maybe twice), after getting the low reservoir warning (under 20U on my Accu-Chek pumps), and then forgetting about it because I was deeply engaged in another task. Plus, 20U will typically last 2/3 of the day.
I am typically thankful when these type of errors happen, because they are relatively easy to fix, as opposed to an unexplained high with all systems “Go!”, but seemingly no results!