Ahh, the Cleo!
I will do a comparison between the Inset and the Cleo, and the good/bad of each:
The Inset is pretty nice and easy, with the self enclosed spring loaded thingy (that's an engineering term...) makes insertion pretty easy, once you get the hang of it. The steps are:
1. Open it up
2. Unwrap the tubing*
3. Remove the adhesive paper (that's fun when it tears)
4. Remove the needle protector
5. Arm the inserter (thingy)
6. Press against your body and squeeze the sides to insert it. (make sure the angle of the tubing is how you like it)
7. Fill up the tubing, and click it to the infusion set.
1. Unscrew the top.
2. The adhesion pad is already exposed, and so you're good to go there. (see #3 above)
3. Press against your body, and press the "plunger" to insert the canula.
4. Count to 5. I heard a "click" after about 5 seconds. This is the first time I've used them, and there was no mention of any clicking, so I'll let you know. The 5 seconds is important, as the adhesive is heat activated (as I've been told by Robyn over at Tandem), so I don't want to have it fall out. 5 seconds it is.
5. The tubing is separate from the infusion set, and that can be good/bad. I know that I'm the first diabetic to re-use their tubing, so I look at it as an advantage. I can use tubing/infusion sets independent of each other. Fill it and a attach it. Note: the tubing is 8 position, not 360 degrees. I only mention it as these things need to be corrected. It's a small point, but a point nonetheless.
Insertion winner: It's a tie. I could go with either one. If I were grabbing my stuff and running to the mountains due to a zombie attack, the Insets would be my choice, since the tubing is included in the set. However, since there is no imminent zombie apocalypse, I like the separate tubing, in its own package.
Packaging: If you don't like to throw things away, go with the Inset. There is less waste. The inserter with the Cleo is pretty bulky, but it does protect the inserter rather well. You can put either in your pocket, and you'll be good to go. There is one advantage to the Cleo: If you have a purse/backpack with pens/pointy things in it, go with the Cleo. The infusion set is covered by hard plastic, so nothing will penetrate it, unless it really wants to.
Comfort: Since I have been wearing the Cleo for about 45 minutes, it's a wash. I don't feel infusion sets after they're in, and the Cleo is no different.
Removal: I will have to get back to you on this. I will post back here if it pulls itself out, or doesn't adhere well. The Insets have not had this problem (1-3x per year, and it was incidental, not random).
One last note: Cleos are made by Smiths Medical, the same people that make the Cozmo. A demo can be found here: